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liaF [2019-06-06 09:44:59]
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liaF [2019-06-06 09:44:59]

inhibitor of LiaS kinase activity
Locus
BSU33100
Isoelectric point
9.21
Molecular weight
26.88 kDa
Protein length
241 aa Sequence Blast
Gene length
726 bp Sequence Blast
Function
control of LiaR activity
Product
negative effector of LiaS
Essential
no
Synonyms
yvqF

Genomic Context

      
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Categories containing this gene/protein

Gene

Coordinates
3,396,114 → 3,396,839

The protein

Catalyzed reaction/ biological activity

  • inhibitor of LiaS kinase activity, maintains LiaS in the phosphatase state in the absence of the stress signal PubMed
  • Localization

  • cell membrane (according to Swiss-Prot)
  • Expression and Regulation

    Operons

    Description

    Sigma factors

  • SigA: sigma factor, PubMed, in SigA regulon
  • Regulatory mechanism

  • LiaR: activation, PubMed, in LiaR regulon
  • Regulation

  • liaG: constitutive
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    Description

    Regulation

  • liaG: constitutive
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    Biological materials

    Mutant

  • MGNA-B037 (yvqF::erm), available at the NBRP B. subtilis, Japan
  • BKE33100 (ΔliaF::erm trpC2) available at BGSC, PubMed, upstream reverse: _UP1_CATTCCTGGTGTCCGCCTCC, downstream forward: _UP4_GGTGATGTGGATGTGAAGTA
  • BKK33100 (ΔliaF::kan trpC2) available at BGSC, PubMed, upstream reverse: _UP1_CATTCCTGGTGTCCGCCTCC, downstream forward: _UP4_GGTGATGTGGATGTGAAGTA
  • References

    Reviews

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    Original publications

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